2756250-30-1
Chemical Structure
Nav1.8-IN-2
- CAS No.: 2756250-30-1
- Formula:C18H13Cl2F3N2O3
- Molecular Weight:433.21
IUPAC Name: (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-(methyl-d3)hept-5-en-2-yl-7,7,7-d3)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: AHMFIVOVWPKBNX-GJZGRUSLSA-N
SMILES: O=C([C@H]1OC(NC1)=O)N[C@@H](C2=CC=C(C=C2)Cl)C3=CC(C(F)(F)F)=C(C=C3)Cl
Biological Activity: Nav1.8-IN-2 (compound 35A) is a Nav1.8 voltage-gated sodium ion inhibitor with an IC50 of 0.4 nM (HEK 293 cells). Nav1.8-IN-2 inhibits the activity of Nav1.8 voltage-gated sodium ion channels, mediates sodium ion influx in excitable cells, and is associated with the initiation and conduction of action potentials. Nav1.8-IN-2 can be used for research related to pain, cough, itching, etc[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nav1.8-IN-2 | 99.83% | Nav1.8-IN-2 (compound 35A) is a Nav1.8 voltage-gated sodium ion inhibitor with an IC50 of 0.4 nM (HEK 293 cells). Nav1.8-IN-2 inhibits the activity of Nav1.8 voltage-gated sodium ion channels, mediates sodium ion influx in excitable cells, and is associated with the initiation and conduction of action potentials. Nav1.8-IN-2 can be used for research related to pain, cough, itching, etc. | ||||||||||||||||||||
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