2756855-66-8
2756855-66-8
Chemical Structure
Lp-PLA2-IN-14
- CAS No.: 2756855-66-8
- Formula:C16H14F3N3O3
- Molecular Weight:353.30
IUPAC Name: 9-((3,4,5-trifluorobenzyl)oxy)-2,3,5,6-tetrahydro-4H,7H-1-oxa-3a,6a,8-triazaphenalen-7-one
InChIKey: XFEWOHBVSRKLGJ-UHFFFAOYSA-N
SMILES: O=C1N=C(C2=C(N1CCC3)N3CCO2)OCC4=CC(F)=C(C(F)=C4)F
Biological Activity: Lp-PLA2-IN-14 (Compound 19) is an Lp-PLA2 inhibitor with a pIC50 of 8.4 against rhLp-PLA2. Lp-PLA2-IN-14 can be used for the research of neurodegenerative related diseases, such as Alzheimer Disease (AD), glaucoma, age-related macular degeneration (AMD) or cardiovascular diseases including atherosclerosis and the like[1].
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Lp-PLA2-IN-14 | Lp-PLA2-IN-14 (Compound 19) is an Lp-PLA2 inhibitor with a pIC50 of 8.4 against rhLp-PLA2. Lp-PLA2-IN-14 can be used for the research of neurodegenerative related diseases, such as Alzheimer Disease (AD), glaucoma, age-related macular degeneration (AMD) or cardiovascular diseases including atherosclerosis and the like. | |||||||||||||||||||||
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