2757292-12-7
Chemical Structure
KSL 128114
- CAS No.: 2757292-12-7
- Formula:C96H165N39O21
- Molecular Weight:2201.59
SMILES: N=C(NCCC[C@H](C(N[C@H](C(N[C@@H](C(NCC(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CC(O)=O)=O)C3CCCCC3)=O)C(C)(C)C)=O)=O)CC4=CN=CN4)=O)CO)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)NC(C)=O)N
Biological Activity: KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin[1].
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KSL 128114 | KSL 128114, a peptide inhibitor of syntenin, binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and displays a global PDZ domain selectivity for syntenin. | |||||||||||||||||||||
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