2757405-31-3
2757405-31-3
Chemical Structure
hDHODH-IN-8
- CAS No.: 2757405-31-3
- Formula:C21H15F6N3O4
- Molecular Weight:487.35
IUPAC Name: (S,Z)-4-(2-cyano-3-hydroxybut-2-enamido)-N-(2,6-difluorophenyl)-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)benzamide
InChIKey: BIDNHWHAWYEYKL-JMZICWNOSA-N
SMILES: FC1=C(NC(/C(C#N)=C(O)/C)=O)C=C(O[C@H](C(F)(F)F)C)C(C(NC2=C(F)C=CC=C2F)=O)=C1
Biological Activity: hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and excellent aqueous solubility. hDHODH-IN-8 has the potential for the research of tumor disease, especially lymphoma[1].
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hDHODH-IN-8 | hDHODH-IN-8 is a potent inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 16 nM. hDHODH-IN-8 has potent antiproliferative activity and excellent aqueous solubility. hDHODH-IN-8 has the potential for the research of tumor disease, especially lymphoma. | |||||||||||||||||||||
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