2760128-48-9
2760128-48-9
Chemical Structure
PPARα/δ agonist 1
- CAS No.: 2760128-48-9
- Formula:C22H22F3N3O5
- Molecular Weight:465.42
IUPAC Name: 2-(2,6-dimethyl-4-((5-oxo-4-(4-(trifluoromethoxy)phenyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl)methyl)phenoxy)-2-methylpropanoic acid
InChIKey: IUEFKAHLCBNPMM-UHFFFAOYSA-N
SMILES: O=C1N(N=CN1C2=CC=C(C=C2)OC(F)(F)F)CC3=CC(C)=C(C(C)=C3)OC(C)(C(O)=O)C
Biological Activity: PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist (PPARα EC50=7.0 nM; PPARδ EC50=8.4 nM). PPARα/δ agonist 1 is a high selectivity over PPARγ (PPARγ EC50=1316.1 nM). PPARα/δ agonist 1 has the potential for the research of nonalcoholic steatohepatitis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PPARα/δ agonist 1 | 99.59% | PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist (PPARα EC50=7.0 nM; PPARδ EC50=8.4 nM). PPARα/δ agonist 1 is a high selectivity over PPARγ (PPARγ EC50=1316.1 nM). PPARα/δ agonist 1 has the potential for the research of nonalcoholic steatohepatitis. | ||||||||||||||||||||
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