2761657-21-8
2761657-21-8
Chemical Structure
STAT3-IN-43
- CAS No.: 2761657-21-8
- Formula:C17H19BrN2O4
- Molecular Weight:395.25
InChIKey: FVNQRDDBVKLZQB-UHFFFAOYSA-N
SMILES: BrC1=CC(CNC(C2CCCN(C(C=C)=O)C2)=O)=CC3=C1OCO3
Biological Activity: STAT3-IN-43 (Compound K2) is a covalent inhibitor targeting the allosteric site at the junction of the STAT3 coiled-coil domain and DNA-binding domain, with an IC50 of 40.7 μM. STAT3-IN-43 can be used in cancer research[1].
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STAT3-IN-43 | STAT3-IN-43 (Compound K2) is a covalent inhibitor targeting the allosteric site at the junction of the STAT3 coiled-coil domain and DNA-binding domain, with an IC50 of 40.7 μM. STAT3-IN-43 can be used in cancer research. | |||||||||||||||||||||
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