2762043-53-6
2762043-53-6
Chemical Structure
BTK-IN-12
- CAS No.: 2762043-53-6
- Formula:C27H28FN5O4
- Molecular Weight:505.54
IUPAC Name: N-(4-(8-amino-3-(6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)imidazo[1,5-a]pyrazin-1-yl)benzyl)-5-fluoro-2-methoxybenzamide
InChIKey: ZIDSHDSDYPAALX-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1C(NCC2=CC=C(C=C2)C3=C4C(N)=NC=CN4C(C5CCC(OC5)CO)=N3)=O)F
Biological Activity: BTK-IN-12 is a potent BTK inhibitor with IC50s of 1.2 nM and 0.8 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022037649A1; compound 8)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BTK-IN-12 | BTK-IN-12 is a potent BTK inhibitor with IC50s of 1.2 nM and 0.8 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022037649A1; compound 8). | |||||||||||||||||||||
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