2762315-06-8
2762315-06-8
Chemical Structure
HIF-1α-IN-2
- CAS No.: 2762315-06-8
- Formula:C21H19N3OS
- Molecular Weight:361.46
IUPAC Name: 7-methoxy-2-methyl-N-(3-(2-methylthiazol-4-yl)phenyl)quinolin-4-amine
InChIKey: ILYYBJSTMKDZND-UHFFFAOYSA-N
SMILES: CC1=NC(C2=CC(NC3=CC(C)=NC4=CC(OC)=CC=C34)=CC=C2)=CS1
Biological Activity: HIF-1α-IN-2 is an effective HIF-1α inhibitor with anticancer potencies (IC50s of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cells, respectively). HIF-1α-IN-2 suppresses HIF-1α expression by blocking transcription and protein translation[1].
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HIF-1α-IN-2 | 98.48% | HIF-1α-IN-2 is an effective HIF-1α inhibitor with anticancer potencies (IC50s of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cells, respectively). HIF-1α-IN-2 suppresses HIF-1α expression by blocking transcription and protein translation. | ||||||||||||||||||||
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