2762547-06-6
Chemical Structure
CD33 splicing modulator 1 hydrochloride
- CAS No.: 2762547-06-6
- Formula:C25H26ClFN6O
- Molecular Weight:480.96
IUPAC Name: (R)-3-fluoro-4-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-methylpyridin-2-yl)-N-(piperidin-3-yl)benzamide hydrochloride
InChIKey: PWORZWDKPPZPIN-FSRHSHDFSA-N
SMILES: CC1=CN2N=CC(C3=CC=C(C=C3F)C(N([C@@H]4CCCNC4)C5=C(C=CC=N5)C)=O)=C2N=C1.[H]Cl
Biological Activity: CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid cell surface receptor known to regulate microglial activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in the cellular mRNA pool and can be used to study neurodegenerative diseases including Alzheimer's disease[1].
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CD33 splicing modulator 1 hydrochloride | CD33 splicing modulator 1 (Compound 1) hydrochloride is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid cell surface receptor known to regulate microglial activity. CD33 splicing modulator 1 hydrochloride increases exon 2 skipping in the cellular mRNA pool and can be used to study neurodegenerative diseases including Alzheimer's disease. | |||||||||||||||||||||
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