2763063-15-4
2763063-15-4
Chemical Structure
Apoptosis inducer 25
- CAS No.: 2763063-15-4
- Formula:C42H53NO7
- Molecular Weight:683.87
InChIKey: ZMIJDIQZMBFQQJ-IVSQANOZSA-N
SMILES: O=C1C(C#N)=C[C@]2([C@]([H])(C1(C)C)CC[C@](C)(C2=CC3=O)[C@]4([C@]3([C@]5([C@@](C(OCCCCOC(C6=CC=C(C=C6)O)=O)=O)(CC4)CCC(C)(C5)C)[H])[H])C)C
Biological Activity: Apoptosis inducer 25 (Compound 4H) inhibits the proliferation of cell BGC-823 with IC50 of 0.37 μM. Apoptosis inducer 25 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 25 exhibits good pharmacokinetic properties in rats[1].
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Apoptosis inducer 25 | Apoptosis inducer 25 (Compound 4H) inhibits the proliferation of cell BGC-823 with IC50 of 0.37 μM. Apoptosis inducer 25 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 25 exhibits good pharmacokinetic properties in rats. | |||||||||||||||||||||
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