2763983-45-3
2763983-45-3
Chemical Structure
JNUTS013
- CAS No.: 2763983-45-3
- Formula:C20H22O6
- Molecular Weight:358.39
InChIKey: PHPARPNDGGXMEO-VOTSOKGWSA-N
SMILES: OC1=C(C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O)C=C(C)C(O)=C1C
Biological Activity: JNUTS013 is a NLRP3 inflammasome inhibitor. JNUTS013 promotes proteasome-dependent degradation of NLRP3 and inhibits the release of downstream cytokines. JNUTS013 downregulates the expression of inflammation-related proteins including iNOS and COX-2. JNUTS013 exhibits anti-inflammatory activity and can be used in the research of inflammatory diseases[1].
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JNUTS013 | JNUTS013 is a NLRP3 inflammasome inhibitor. JNUTS013 promotes proteasome-dependent degradation of NLRP3 and inhibits the release of downstream cytokines. JNUTS013 downregulates the expression of inflammation-related proteins including iNOS and COX-2. JNUTS013 exhibits anti-inflammatory activity and can be used in the research of inflammatory diseases. | |||||||||||||||||||||
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