2765247-36-5
Chemical Structure
HSP90-IN-9
- CAS No.: 2765247-36-5
- Formula:C30H31N3O5
- Molecular Weight:513.58
IUPAC Name: 5-(4,6-dihydroxy-4'-methyl-[1,1'-biphenyl]-3-yl)-N-ethyl-4-(4-(morpholinomethyl)phenyl)isoxazole-3-carboxamide
InChIKey: UDZVCJITJNDSEF-UHFFFAOYSA-N
SMILES: CCNC(C1=NOC(C2=C(C=C(C(C3=CC=C(C=C3)C)=C2)O)O)=C1C4=CC=C(C=C4)CN5CCOCC5)=O
Biological Activity: HSP90-IN-9 is a potent and selective HSP90 inhibitor. HSP90-IN-9 displays a fungicidal effect in a dose-dependent manner. HSP90-IN-9 inhibits fungal biofilm formation and fungal morphological changes after being combined with FLC. HSP90-IN-9 recovers FLC resistance by down-regulating the expression of related genes (ERG11, CDR1 and CDR2)[1].
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HSP90-IN-9 | HSP90-IN-9 is a potent and selective HSP90 inhibitor. HSP90-IN-9 displays a fungicidal effect in a dose-dependent manner. HSP90-IN-9 inhibits fungal biofilm formation and fungal morphological changes after being combined with FLC. HSP90-IN-9 recovers FLC resistance by down-regulating the expression of related genes (ERG11, CDR1 and CDR2). | |||||||||||||||||||||
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