2765296-93-1
2765296-93-1
Chemical Structure
Transthyretin-IN-4
- CAS No.: 2765296-93-1
- Formula:C26H24Cl4N2O7
- Molecular Weight:618.29
SMILES: ClC1=CC(NC2=C(C(O)=O)C=CN=C2)=CC(Cl)=C1OCCOCCCOC3=C(Cl)C=C(CCC(O)=O)C=C3Cl
Biological Activity: Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin (TTR) amyloidosis (bIC50: 0.09 µM, pIC50: 1.4 µM). Transthyretin-IN-4 is used in the study of fatal heart failure with preserved ejection fraction (HFpEF) and fatal arrhythmias[1].
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Transthyretin-IN-4 | Transthyretin-IN-4 (Compound B26) is a bivalent inhibitor of transthyretin (TTR) amyloidosis (bIC50: 0.09 µM, pIC50: 1.4 µM). Transthyretin-IN-4 is used in the study of fatal heart failure with preserved ejection fraction (HFpEF) and fatal arrhythmias. | |||||||||||||||||||||
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