2765535-21-3
2765535-21-3
Chemical Structure
PD-1/PD-L1-IN-32
- CAS No.: 2765535-21-3
- Formula:C29H25ClFN3O3
- Molecular Weight:517.98
InChIKey: DSELNKYPNSPLEU-UHFFFAOYSA-N
SMILES: N#CC1=CC(COC2=C(C=CC(OCC3=C(C(C4=CC=CC=C4F)=CC=C3)Cl)=C2)CNCCO)=CN=C1
Biological Activity: PD-1/PD-L1-IN-32 (compound A56) is a potent PD-1/PD-L1 inhibitor (IC50=2.4 nM), with anticancer activity. PD-1/PD-L1-IN-32 significantly inhibits tumor growth in hPD-L1 MC38 humanized mouse model, without obvious toxicity against mouse normal ability[1].
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PD-1/PD-L1-IN-32 | PD-1/PD-L1-IN-32 (compound A56) is a potent PD-1/PD-L1 inhibitor (IC50=2.4 nM), with anticancer activity. PD-1/PD-L1-IN-32 significantly inhibits tumor growth in hPD-L1 MC38 humanized mouse model, without obvious toxicity against mouse normal ability. | |||||||||||||||||||||
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