2766231-05-2
2766231-05-2
Chemical Structure
EZH2-IN-22
- CAS No.: 2766231-05-2
- Formula:C36H50N4O8
- Molecular Weight:666.80
InChIKey: HFXLGJYNXABHNY-YOAAGGMHSA-N
SMILES: OC(/C=C\C(O)=O)=O.CCN(C1CCOCC1)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(O[C@@H]4C[C@@H](N5CCCCC5)C4)=C2)C
Biological Activity: EZH2-IN-22 (example 92) is a potent EZH2 inhibitor with IC50 values of <0.00051, <0.00051, 0.00052 µM for EZH2 (Y641N), EZH2 (Y641F), EZH2 (wt), respectively. EZH2-IN-22 shows antiproliferation activity[1].
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EZH2-IN-22 | EZH2-IN-22 (example 92) is a potent EZH2 inhibitor with IC50 values of <0.00051, <0.00051, 0.00052 µM for EZH2 (Y641N), EZH2 (Y641F), EZH2 (wt), respectively. EZH2-IN-22 shows antiproliferation activity. | |||||||||||||||||||||
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