2766609-08-7
2766609-08-7
Chemical Structure
S100A2-p53-IN-1
- CAS No.: 2766609-08-7
- Formula:C20H20F6N2O4S
- Molecular Weight:498.44
IUPAC Name: N-(3-(((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)amino)propyl)-3,5-bis(trifluoromethyl)benzenesulfonamide
InChIKey: JYSRREBPWYOTKR-UHFFFAOYSA-N
SMILES: O=S(NCCCNCC1COC2=C(O1)C=CC=C2)(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O
Biological Activity: S100A2-p53-IN-1 (compound 51) is a S100A2-p53 interactions inhibitor. S100A2 is a Ca2+ binding protein with implications in cell signaling and is known to be upregulated in pancreatic cancer. S100A2-p53-IN-1 can inhibit the growth of the MiaPaCa-2 pancreatic cancer cell line (GI50 of 1.2-3.4 μM)[1].
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S100A2-p53-IN-1 | S100A2-p53-IN-1 (compound 51) is a S100A2-p53 interactions inhibitor. S100A2 is a Ca2+ binding protein with implications in cell signaling and is known to be upregulated in pancreatic cancer. S100A2-p53-IN-1 can inhibit the growth of the MiaPaCa-2 pancreatic cancer cell line (GI50 of 1.2-3.4 μM). | |||||||||||||||||||||
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