2766698-38-6
2766698-38-6
Chemical Structure
MU1656
- CAS No.: 2766698-38-6
- Formula:C32H45N7O2
- Molecular Weight:559.75
IUPAC Name: (1R,2S,3S,5R)-3-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-((((1r,3S)-3-(2-(6-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)cyclopentane-1,2-diol
InChIKey: RKRUMZCAPLOLQM-JOMNVXSOSA-N
SMILES: O[C@H]1[C@@H](C[C@@H]([C@H]1O)CN([C@H]2C[C@H](C2)CCC(NC3=C4)=NC3=CC=C4C(C)(C)C)C(C)C)C5=CC=C6N5N=CN=C6N
Biological Activity: MU1656 is a potent and selective inhibitor of histone methyltransferase DOT1L, with an IC50 of 2 nM. MU1656 can be used for the research of hematological malignancies[1].
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MU1656 | MU1656 is a potent and selective inhibitor of histone methyltransferase DOT1L, with an IC50 of 2 nM. MU1656 can be used for the research of hematological malignancies. | |||||||||||||||||||||
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