2768265-58-1
2768265-58-1
Chemical Structure
Aha1/Hsp90-IN-1
- CAS No.: 2768265-58-1
- Formula:C22H17F3N4O2
- Molecular Weight:426.39
IUPAC Name: 5-(3',6-dimethoxy-[1,1'-biphenyl]-3-yl)-1-(4-(trifluoromethyl)phenyl)-1H-tetrazole
InChIKey: DFAYTMMBPZGUIS-UHFFFAOYSA-N
SMILES: COC1=CC(C2=C(C=CC(C3=NN=NN3C4=CC=C(C=C4)C(F)(F)F)=C2)OC)=CC=C1
Biological Activity: Aha1/Hsp90-IN-1 (Compound 17) is an Aha1/Hsp90 complex inhibitor. Aha1/Hsp90-IN-1 disrupts Aha1/Hsp90 interactions with an IC50 of 3.32 μM. Aha1/Hsp90-IN-1 inhibits tau aggregation[1].
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Aha1/Hsp90-IN-1 | Aha1/Hsp90-IN-1 (Compound 17) is an Aha1/Hsp90 complex inhibitor. Aha1/Hsp90-IN-1 disrupts Aha1/Hsp90 interactions with an IC50 of 3.32 μM. Aha1/Hsp90-IN-1 inhibits tau aggregation. | |||||||||||||||||||||
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