2769753-69-5
Chemical Structure
DD-03-156
Synonym(s): (S,R,S)-AHPC-Me-PEG2-dabrafenib
- CAS No.: 2769753-69-5
- Formula:C53H62F3N9O8S3
- Molecular Weight:1106.31
IUPAC Name: (2S,4R)-1-((S)-2-(3-(2-(2-((4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidin-2-yl)amino)ethoxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
InChIKey: BMLDGVCSNFURAJ-QUQZIOAQSA-N
SMILES: CC(C)(C)C(S1)=NC(C2=CC=CC(NS(C3=C(F)C=CC=C3F)(=O)=O)=C2F)=C1C4=NC(NCCOCCOCCC(N[C@@H](C(C)(C)C)C(N5C[C@H](O)C[C@H]5C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)=O)=NC=C4
Biological Activity: DD-03-156 ((S,R,S)-AHPC-Me-PEG2-dabrafenib) is a VHL-based PROTAC degrader targeting CDK17 and LIMK2. DD-03-156 serves as an excellent lead-like starting point for the development of selective chemical probes targeting CDK17 degradation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DD-03-156 | 99.90% | DD-03-156 ((S,R,S)-AHPC-Me-PEG2-dabrafenib) is a VHL-based PROTAC degrader targeting CDK17 and LIMK2. DD-03-156 serves as an excellent lead-like starting point for the development of selective chemical probes targeting CDK17 degradation. | ||||||||||||||||||||
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