2770681-85-9
2770681-85-9
Chemical Structure
TRβ agonist 1
- CAS No.: 2770681-85-9
- Formula:C29H25FN2O8
- Molecular Weight:548.52
IUPAC Name: (7-(4-(3-fluoro-5-methoxybenzoyl)-2,6-dimethylphenoxy)-4-hydroxy-1-methoxyisoquinoline-3-carbonyl)glycine
InChIKey: CRBPLLHXFFMVKV-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(C=C2C(OC)=N1)OC3=C(C=C(C=C3C)C(C4=CC(OC)=CC(F)=C4)=O)C)O)NCC(O)=O
Biological Activity: TRβ agonist 1 is a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, with an EC50 value of 21 nM. TRβ agonist 1 can be used for researching dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH)[1].
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TRβ agonist 1 | TRβ agonist 1 is a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, with an EC50 value of 21 nM. TRβ agonist 1 can be used for researching dyslipidemia, nonalcoholic steatohepatitis (NASH), and resistance to thyroid hormone (RTH). | |||||||||||||||||||||
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