2770911-29-8
2770911-29-8
Chemical Structure
ER degrader 11
- CAS No.: 2770911-29-8
- Formula:C29H33F3N4
- Molecular Weight:494.59
InChIKey: MOYJTIZSTKNDGD-OEVYRDLRSA-N
SMILES: C[C@H](CC1=C2NC3=CC=CC=C31)N([C@@H]2C4=C(C=C(C=C4F)NC5CN(C5)CCCF)F)C67CC(C7)C6
Biological Activity: ER degrader 11 (Compound 5) is an orally active, brain-penetrant and selective estrogen receptor (ER) degrader (ERα IC50=1.6 nM). ER degrader 11 is promising for research of breast cancer brain metastasis[1].
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ER degrader 11 | ER degrader 11 (Compound 5) is an orally active, brain-penetrant and selective estrogen receptor (ER) degrader (ERα IC50=1.6 nM). ER degrader 11 is promising for research of breast cancer brain metastasis. | |||||||||||||||||||||
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