2771021-30-6
2771021-30-6
Chemical Structure
NLRP3-IN-95
- CAS No.: 2771021-30-6
- Formula:C16H11F4IN4O2
- Molecular Weight:494.18
InChIKey: HPCCPHXTPHJJCJ-UHFFFAOYSA-N
SMILES: O=C(CN1C(C2=CC=C(C=C2C(C(F)(F)F)C1)I)=O)NC3=NC=C(C=N3)F
Biological Activity: NLRP3-IN-95 is an NLRP3 inflammasome inhibitor with an IC50 of 27 nM. NLRP3-IN-95 inhibits IL-1β secretion in PMA-differentiated THP-1 cells. NLRP3-IN-95 can be used in studies related to acute monocytic leukemia and inflammatory diseases[1].
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NLRP3-IN-95 | NLRP3-IN-95 is an NLRP3 inflammasome inhibitor with an IC50 of 27 nM. NLRP3-IN-95 inhibits IL-1β secretion in PMA-differentiated THP-1 cells. NLRP3-IN-95 can be used in studies related to acute monocytic leukemia and inflammatory diseases. | |||||||||||||||||||||
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