2773428-48-9
2773428-48-9
Chemical Structure
FerroLOXIN-1
- CAS No.: 2773428-48-9
- Formula:C23H16F5N3
- Molecular Weight:429.39
InChIKey: TZTVXYFOBQIIBL-UHFFFAOYSA-N
SMILES: FC1=CC=CC(N2C=C(C3=CC=CC=C3)N=C2NCC4=CC=C(C(F)(F)F)C(F)=C4)=C1
Biological Activity: FerroLOXIN-1 is a potent inhibitor of 15LOX-2 that selectively blocked production of pro-ferroptotic HOO-ETE-PE and protected against RSL3-induced ferroptosis. FerroLOXIN-1 closely interacted therein with 15LOX-2 only, and in particular with Y154, N155, W158[1].
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FerroLOXIN-1 | FerroLOXIN-1 is a potent inhibitor of 15LOX-2 that selectively blocked production of pro-ferroptotic HOO-ETE-PE and protected against RSL3-induced ferroptosis. FerroLOXIN-1 closely interacted therein with 15LOX-2 only, and in particular with Y154, N155, W158. | |||||||||||||||||||||
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