2775428-94-7
2775428-94-7
Chemical Structure
Antitumor agent-183
- CAS No.: 2775428-94-7
- Formula:C31H18D15BrN4O9
- Molecular Weight:700.61
InChIKey: IPNJNCWSYYYTQE-RMIIKSHTSA-N
SMILES: O=C(N[C@H]1CC(N(OC([2H])([2H])[2H])C([2H])([2H])[2H])=O)C2=CC(OC3=CC(C)=CC(C)=C3)=C(C=C2NC1=O)NC(C4=C(C(OC([2H])([2H])[2H])=C(C(OC([2H])([2H])[2H])=C4)OC([2H])([2H])[2H])Br)=O
Biological Activity: Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues[1].
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Antitumor agent-183 | Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues. | |||||||||||||||||||||
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