2775441-10-4
Chemical Structure
ERα degrader 6
- CAS No.: 2775441-10-4
- Formula:C28H23F3N4O4S
- Molecular Weight:568.57
IUPAC Name: (1R,2S,4R)-6-(4-(1H-1,2,4-triazol-1-yl)phenyl)-5-(4-hydroxyphenyl)-N-phenyl-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide
InChIKey: KVXXNOUZPPJCEE-DXBVXKBHSA-N
SMILES: O=S([C@@H]1[C@H]2C(C3=CC=C(N4C=NC=N4)C=C3)=C(C5=CC=C(O)C=C5)[C@H](O2)C1)(N(CC(F)(F)F)C6=CC=CC=C6)=O
Biological Activity: ERα degrader 6 is a selective dual-targeting estrogen receptor α (ERα) degrader. ERα degrader 6 induces ERα degradation, aromatase inhibition, and exerts antiproliferative effects in endocrine-resistant breast cancer cells. ERα degrader 6 can be used for research related to endocrine-resistant breast cancer[1].
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ERα degrader 6 | ERα degrader 6 is a selective dual-targeting estrogen receptor α (ERα) degrader. ERα degrader 6 induces ERα degradation, aromatase inhibition, and exerts antiproliferative effects in endocrine-resistant breast cancer cells. ERα degrader 6 can be used for research related to endocrine-resistant breast cancer. | |||||||||||||||||||||
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