2780391-08-2
2780391-08-2
Chemical Structure
G3-YSD
- CAS No.: 2780391-08-2
- Formula:N/A
- Molecular Weight:8088.29
SMILES: [DNA, d(G-G-G-T-A-T-A-T-A-T-A-T-G-C-A-T-A-T-A-T-A-T-A-G-G-G)]
Biological Activity: G3-YSD is a cGAS agonist. G3-YSD directly interacts with cGAS to enhance its enzymatic activity, promote the conversion of ATP and GTP into cGAMP, and trigger STING-dependent IFN-α/β secretion. G3-YSD acts as a viral mimic to replace actual viral DNA. G3-YSD is applicable to research related to long COVID and type 1 human immunodeficiency virus infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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G3-YSD | 98.37% | G3-YSD is a cGAS agonist. G3-YSD directly interacts with cGAS to enhance its enzymatic activity, promote the conversion of ATP and GTP into cGAMP, and trigger STING-dependent IFN-α/β secretion. G3-YSD acts as a viral mimic to replace actual viral DNA. G3-YSD is applicable to research related to long COVID and type 1 human immunodeficiency virus infection. | ||||||||||||||||||||
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References
- [1]. Humer B, et al. Exaggerated IFN-I Response in Long COVID PBMCs Following Exposure to Viral Mimics. J Clin Immunol. 2025;46(1):5. Published 2025 Dec 10. [Content Brief]
- [2]. Herzner AM, et al. Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA. Nat Immunol. 2015;16(10):1025-1033. [Content Brief]
