2787582-17-4
Chemical Structure
TP0556351
- CAS No.: 2787582-17-4
- Formula:C50H70N10O16
- Molecular Weight:1067.15
IUPAC Name: (4S,7S,10S,13S,16S)-4-((S)-2-(2-amino-2-oxoethyl)pyrrolidine-1-carbonyl)-10-(2-aminoethyl)-16-(5-(4-(4-carbamoylphenoxy)benzamido)pentanamido)-13-(carboxymethyl)-7-isobutyl-5-methyl-6,9,12,15-tetraoxo-5,8,11,14-tetraazanonadecanedioic acid
InChIKey: FVDPKGPPYGTKTO-DLXWRWKMSA-N
SMILES: CC(C[C@@H](C(N([C@H](C(N1CCC[C@H]1CC(N)=O)=O)CCC(O)=O)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCNC(C2=CC=C(OC3=CC=C(C(N)=O)C=C3)C=C2)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CCN)=O)C
Biological Activity: TP0556351 is a potent and selective matrix metalloproteinase-2 (MMP2) inhibitor with an IC50 value of 0.2 nM. TP0556351 reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model. TP0556351 can be used for researching idiopathic pulmonary fibrosis (IPF)[1].
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TP0556351 | TP0556351 is a potent and selective matrix metalloproteinase-2 (MMP2) inhibitor with an IC50 value of 0.2 nM. TP0556351 reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model. TP0556351 can be used for researching idiopathic pulmonary fibrosis (IPF). | |||||||||||||||||||||
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