2790482-16-3
2790482-16-3
Chemical Structure
(±)-trans-BAS-2
- CAS No.: 2790482-16-3
- Formula:C13H21N3O2S
- Molecular Weight:283.39
InChIKey: YKWHALHXTMWCPC-QWRGUYRKSA-N
SMILES: [H][C@@]12[C@](NC(SCC(N3CCOCC3)=O)=N2)([H])CCCC1
Biological Activity: (±)-trans-BAS-2 is a hHDAC6 inhibitor with an IC50 value of 0.462 μM. (±)-trans-BAS-2 serves as a scaffold for the design of proteolysis-targeting chimeras (PROTACs) and induces proteasome-dependent degradation of hHDAC6 in cells. (±)-trans-BAS-2 can be used in the research of triple-negative breast cancer and multiple myeloma[1].
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(±)-trans-BAS-2 | (±)-trans-BAS-2 is a hHDAC6 inhibitor with an IC50 value of 0.462 μM. (±)-trans-BAS-2 serves as a scaffold for the design of proteolysis-targeting chimeras (PROTACs) and induces proteasome-dependent degradation of hHDAC6 in cells. (±)-trans-BAS-2 can be used in the research of triple-negative breast cancer and multiple myeloma. | |||||||||||||||||||||
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