2792146-91-7
2792146-91-7
Chemical Structure
DNA-PK-IN-12
- CAS No.: 2792146-91-7
- Formula:C21H24N8O2
- Molecular Weight:420.47
InChIKey: GDKSDPBBGUPQCM-UHFFFAOYSA-N
SMILES: O=C1N(C)C2=CN=C(NC3=C(C)C=C(C4=CN(C)N=C4)N=C3)N=C2N1C5CCOCC5
Biological Activity: DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. DNA-PK-IN-12 inhibits cell growth and Hct116 cell colony formation with the IC50 of 33.28 μM, and shows antitumor activity in vivo[1].
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DNA-PK-IN-12 | 99.63% | DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0.1 nM. DNA-PK-IN-12 inhibits cell growth and Hct116 cell colony formation with the IC50 of 33.28 μM, and shows antitumor activity in vivo. | ||||||||||||||||||||
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