2795275-59-9
Chemical Structure
KRAS degrader-1
- CAS No.: 2795275-59-9
- Formula:C55H57Br2ClFIN8O7
- Molecular Weight:1283.25
InChIKey: LOEMJPPVFFSXHV-FXFGZECXSA-N
SMILES: BrC(C=C(C=C1Br)/C=C2C3=CC(I)=CC=C3NC/2=O)=C1OCCOCCOCCOCCCN(CCC4)[C@@H]4COC5=NC(N6C[C@@H](N(CC6)C(C(F)=C)=O)CC#N)=C7C(CN(C8=CC=CC9=C8C(Cl)=CC=C9)CC7)=N5
Biological Activity: KRAS degrader-1 is a potent KRAS degrader. KRAS degrader-1 targets specific proteins for degradation via the autophagy-lysosomal degradation pathway. KRAS degrader-1 is suitable for use in cancer research. (Blue: KRAS G12C-IN-72 (HY-128414); Black: Linker (HY-175587); Pink: 5-Iodoindolin-2-one (HY-76986); Blue + Black: KRAS ligand-Linker Conjugate 7 (HY-175586))[1].
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KRAS degrader-1 | KRAS degrader-1 is a potent KRAS degrader. KRAS degrader-1 targets specific proteins for degradation via the autophagy-lysosomal degradation pathway. KRAS degrader-1 is suitable for use in cancer research. (Blue: KRAS G12C-IN-72 (HY-128414); Black: Linker (HY-175587); Pink: 5-Iodoindolin-2-one (HY-76986); Blue + Black: KRAS ligand-Linker Conjugate 7 (HY-175586)). | |||||||||||||||||||||
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