2801702-34-9

Cyano-myracrylamide Chemical Structure
2801702-34-9

Chemical Structure

Cyano-myracrylamide

  • CAS No.: 2801702-34-9
  • Formula:C19H34N2O
  • Molecular Weight:306.49

InChIKey: RIIUZCPEMOKUSJ-UHFFFAOYSA-N

SMILES: N#CCN(CCCCCCCCCCCCCC)C(C=C)=O

Biological Activity: Cyano-myracrylamide is a broad-spectrum S-acyltransferase/zDHHC inhibitor with an IC50 of 1.35 μM against human zDHHC20. Cyano-myracrylamide covalently binds to DHHC family proteins through its cyanomethyl and acrylamide warheads, thereby blocking the lipid transfer processes such as palmitoylation of their substrate proteins (CD36, GobX, Myd88, Ras, and EGFR). Cyano-myracrylamide can be used in research on type 2 diabetes, lymphoma, and antiphospholipid syndrome[1][2][3][4][5][6].

Cat. No. Product Name Purity Description Pricing
HY-155938 		Cyano-myracrylamide 98.13% Cyano-myracrylamide is a broad-spectrum S-acyltransferase/zDHHC inhibitor with an IC50 of 1.35 μM against human zDHHC20. Cyano-myracrylamide covalently binds to DHHC family proteins through its cyanomethyl and acrylamide warheads, thereby blocking the lipid transfer processes such as palmitoylation of their substrate proteins (CD36, GobX, Myd88, Ras, and EGFR). Cyano-myracrylamide can be used in research on type 2 diabetes, lymphoma, and antiphospholipid syndrome.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References

Keywords