28028-62-8
28028-62-8
Chemical Structure
Ethyl (E)-ferulate
- CAS No.: 28028-62-8
- Formula:C12H14O4
- Molecular Weight:222.24
IUPAC Name: ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
InChIKey: ATJVZXXHKSYELS-FNORWQNLSA-N
SMILES: CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O
Biological Activity: Ethyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].
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Ethyl (E)-ferulate | Ethyl (E)-ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide (HY-D1056)-induced acute lung injury. Additionally, Ethyl (E)-ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E)-ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases. | |||||||||||||||||||||
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References
- [1]. Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42(12):2069-2081. [Content Brief]
- [2]. Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19(6): 8124-8139. [Content Brief]
- [3]. Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29(2):73-83. [Content Brief]
