2816993-09-4
2816993-09-4
Chemical Structure
Anti-inflammatory agent 33
- CAS No.: 2816993-09-4
- Formula:C22H15N3O5S
- Molecular Weight:433.44
IUPAC Name: N-(6,12-dioxo-6,12-dihydroindolo[2,1-b]quinazolin-2-yl)-4-methoxybenzenesulfonamide
InChIKey: RUBUZZAEHSAEGN-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)S(=O)(NC2=CC3=C(N=C4C(C5=CC=CC=C5N4C3=O)=O)C=C2)=O
Biological Activity: Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity[1].
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Anti-inflammatory agent 33 | Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity. | |||||||||||||||||||||
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