2819989-67-6
2819989-67-6
Chemical Structure
PBRM1-BD2-IN-6
- CAS No.: 2819989-67-6
- Formula:C16H15ClN2O
- Molecular Weight:286.76
IUPAC Name: N-((S)-1-(2-((R)-2-chloro-2-fluoroacetyl)-2-(((S)-2-oxopyrrolidin-3-yl)methyl)hydrazinyl)-4-methyl-1-oxopentan-2-yl)-4-fluoro-1H-indole-2-carboxamide
InChIKey: VQRNXAWCBAQDHZ-UHFFFAOYSA-N
SMILES: O=C1NC(C2=CC=CC(C)=C2C)NC3=C1C(Cl)=CC=C3
Biological Activity: PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC50 value of 0.22 μM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer[1].
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PBRM1-BD2-IN-6 | PBRM1-BD2-IN-6 is a potent PBRM1 bromodomain inhibitor with an IC50 value of 0.22 μM. PBRM1-BD2-IN-6 shows antiproliferation activity. PBRM1-BD2-IN-6 has the potential for the research of PBRM1-dependent cancer. | |||||||||||||||||||||
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