2820244-59-3
2820244-59-3
Chemical Structure
TYM-3-98
- CAS No.: 2820244-59-3
- Formula:C28H23ClFN7O3S
- Molecular Weight:592.04
InChIKey: NKLIITQXKFRLOS-UHFFFAOYSA-N
SMILES: COC1=C(F)C=C(C2=NN(C(C)C3=NN(C4=CC=CC(S(C)(=O)=O)=C4)C5=CC(Cl)=CC=C53)C6=C2C(N)=NC=N6)C=C1
Biological Activity: TYM-3-98 is a selective inhibitor for PI3Kδ, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TYM-3-98 | 99.56% | TYM-3-98 is a selective inhibitor for PI3Kδ, with an IC50 of 7.1 nM. TYM-3-98 inhibits proliferationso of B-lymphoma cells. TYM-3-98 inhibits PI3K/AKT/mTOR signaling pathway through induction of apoptosis. TYM-3-98 exhibits good pahrmacokinetic characters and antitumor efficacy in mouse/rat model, without significant toxicity. | ||||||||||||||||||||
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