2820337-96-8
Chemical Structure
AM8936
- CAS No.: 2820337-96-8
- Formula:C25H33NO3
- Molecular Weight:395.53
IUPAC Name: 6-(1-((6aR,10aR)-1-hydroxy-6,6-dimethyl-9-oxo-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl)cyclobutyl)hexanenitrile
InChIKey: VKMKNDIXGCZXCH-WOJBJXKFSA-N
SMILES: CC1(OC2=C([C@@H]3CC(CC[C@H]31)=O)C(O)=CC(C4(CCC4)CCCCCC#N)=C2)C
Biological Activity: AM8936 acts as a balanced and potent cannabinoid receptor type-1 (CB1) agonist in functional assays (EC50s of 8.6 and 1.4 nM for rCB1 and hCB1, respectively). AM8936 exhibits high affinity for rat CB1 (rCB1) with Ki of 0.55 nM. AM8936 is a potent and efficacious CB1 agonist in vivo. AM8936 can be used for the research of CNS and metabolic disorders, pain, glaucoma, etc[1].
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AM8936 | AM8936 acts as a balanced and potent cannabinoid receptor type-1 (CB1) agonist in functional assays (EC50s of 8.6 and 1.4 nM for rCB1 and hCB1, respectively). AM8936 exhibits high affinity for rat CB1 (rCB1) with Ki of 0.55 nM. AM8936 is a potent and efficacious CB1 agonist in vivo. AM8936 can be used for the research of CNS and metabolic disorders, pain, glaucoma, etc. | |||||||||||||||||||||
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