2821068-07-7
2821068-07-7
Chemical Structure
LSD1/2-IN-3
- CAS No.: 2821068-07-7
- Formula:C9H8BrF2N
- Molecular Weight:248.07
IUPAC Name: (1R,2R)-2-(4-bromo-3,5-difluorophenyl)cyclopropan-1-amine
InChIKey: VEESSMHTAMEHGS-SVGQVSJJSA-N
SMILES: N[C@@H]1C[C@@H]1C2=CC(F)=C(Br)C(F)=C2
Biological Activity: LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 11 nM instead of 7 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation[1].
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LSD1/2-IN-3 | LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a Ki value of 11 nM instead of 7 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation. | |||||||||||||||||||||
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