2821068-09-9
2821068-09-9
Chemical Structure
LSD1/2-IN-4
- CAS No.: 2821068-09-9
- Formula:C9H8BrF2N
- Molecular Weight:248.07
IUPAC Name: (1R,2S)-2-(4-bromo-3,5-difluorophenyl)cyclopropan-1-amine
InChIKey: VEESSMHTAMEHGS-YLWLKBPMSA-N
SMILES: N[C@@H]1C[C@H]1C2=CC(F)=C(Br)C(F)=C2
Biological Activity: LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL)[1].
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LSD1/2-IN-4 | LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL). | |||||||||||||||||||||
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