2825567-71-1
2825567-71-1
Chemical Structure
Cathepsin C-IN-3
- CAS No.: 2825567-71-1
- Formula:C28H21F3N6OS
- Molecular Weight:546.57
IUPAC Name: N-(4-(2-((5-(thiophen-3-yl)pyridin-2-yl)amino)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidin-5-yl)phenyl)acetamide
InChIKey: IKADAAAFTZQKFR-UHFFFAOYSA-N
SMILES: CC(NC1=CC=C(C=C1)C2=C(N=C(N=C2)NC3=NC=C(C=C3)C4=CSC=C4)NC5=CC(C(F)(F)F)=CC=C5)=O
Biological Activity: Cathepsin C-IN-3 (compound SF11) is a potent Cathepsin C (Cat C) inhibitor, with an IC50 of 61.79 nM. Cathepsin C-IN-3 also inhibits THP-1 and U937 cell, with IC50 values of 101.5 and 86.5 nM, respectively[1].
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Cathepsin C-IN-3 | Cathepsin C-IN-3 (compound SF11) is a potent Cathepsin C (Cat C) inhibitor, with an IC50 of 61.79 nM. Cathepsin C-IN-3 also inhibits THP-1 and U937 cell, with IC50 values of 101.5 and 86.5 nM, respectively. | |||||||||||||||||||||
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