2826221-10-5
2826221-10-5
Chemical Structure
HIF-1α-IN-5
- CAS No.: 2826221-10-5
- Formula:C16H15N3O2
- Molecular Weight:281.31
IUPAC Name: N-(4-(dimethylamino)phenyl)benzo[d]isoxazole-3-carboxamide
InChIKey: AFVFBXTUFOBKBU-UHFFFAOYSA-N
SMILES: O=C(C1=NOC2=CC=CC=C12)NC3=CC=C(N(C)C)C=C3
Biological Activity: HIF-1α-IN-5 is a HIF-1α inhibitor with an IC50 value of 24 nM (in HEK293T cell). HIF-1α-IN-5 also inhibits MAO-A activity. HIF-1α-IN-5 downregulates VEGF and PDK1 mRNA expressions under hypoxia. HIF-1α-IN-5 can be used in the research of cancer[1].
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HIF-1α-IN-5 | 99.95% | HIF-1α-IN-5 is a HIF-1α inhibitor with an IC50 value of 24 nM (in HEK293T cell). HIF-1α-IN-5 also inhibits MAO-A activity. HIF-1α-IN-5 downregulates VEGF and PDK1 mRNA expressions under hypoxia. HIF-1α-IN-5 can be used in the research of cancer. | ||||||||||||||||||||
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