2826234-37-9
2826234-37-9
Chemical Structure
EZH2-IN-18
- CAS No.: 2826234-37-9
- Formula:C24H20BrN3O3
- Molecular Weight:478.34
InChIKey: FWUSKFGOQPGORO-UHFFFAOYSA-N
SMILES: O=C1C(CNC(C2=CC(C3=CC=C(Br)C=C3)=CC(N4)=C2C=CC4=O)=O)=C(C)C=C(C)N1
Biological Activity: EZH2-IN-18 (compound 9e) is a potent inhibitor of enhancer of zeste homologue 2 (EZH2WT) , with the IC50 of 1.01 nM. EZH2-IN-18 shows inhibition in proliferation and induction in apoptosis in tumor cells[1].
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EZH2-IN-18 | EZH2-IN-18 (compound 9e) is a potent inhibitor of enhancer of zeste homologue 2 (EZH2WT) , with the IC50 of 1.01 nM. EZH2-IN-18 shows inhibition in proliferation and induction in apoptosis in tumor cells. | |||||||||||||||||||||
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