283176-41-0
283176-41-0
Chemical Structure
(E)-Tadehaginoside
- CAS No.: 283176-41-0
- Formula:C21H22O10
- Molecular Weight:434.39
SMILES: OC(C=C1)=CC=C1/C=C/C(OC[C@H]([C@H]([C@@H]([C@H]2O)O)O)O[C@H]2OC3=CC(O)=CC(O)=C3)=O
Biological Activity: (E)-Tadehaginoside is the E-isomer of Tadehaginoside (HY-N15691). Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes[1][2].
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(E)-Tadehaginoside | (E)-Tadehaginoside is the E-isomer of Tadehaginoside (HY-N15691). Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes. | |||||||||||||||||||||
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References
- [1]. Tang A, et al. Antihepatotoxic effect of tadehaginoside, extracted from Tadehagi triquetrum (L.), against CCl4-lesioned rats through activating the Nrf2 signaling pathway and attenuating the inflammatory response. Inflammation. 2014 Aug;37(4):1006-14. [Content Brief]
- [2]. Zhang X, et al. Tadehaginoside modulates lipogenesis and glucose consumption in HepG2 cells. Nat Prod Res. 2015;29(24):2287-90. [Content Brief]
