2839104-01-5
2839104-01-5
Chemical Structure
VEGFR-2-IN-13
- CAS No.: 2839104-01-5
- Formula:C24H18N6O2S
- Molecular Weight:454.50
IUPAC Name: 4-(2-([1,2,4]triazolo[4,3-a]quinoxalin-4-ylthio)acetamido)-N-phenylbenzamide
InChIKey: PXFDSDWTTASZNC-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)C(NC2=CC=CC=C2)=O)CSC3=NC4=C(N5C=NN=C35)C=CC=C4
Biological Activity: VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor with an IC50 of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and induces apoptosis[1].
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VEGFR-2-IN-13 | VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor with an IC50 of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and induces apoptosis. | |||||||||||||||||||||
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