2839447-07-1
2839447-07-1
Chemical Structure
Duazomycin sodium
Synonym(s): Duazomycin A sodium
- CAS No.: 2839447-07-1
- Formula:C8H10N3NaO4
- Molecular Weight:235.17
SMILES: [N-]=[N+]=CC(CC[C@@H](C(O[Na])=O)NC(C)=O)=O
Biological Activity: Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity[1][2].
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Duazomycin sodium | 99.11% | Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity. | ||||||||||||||||||||
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Duazomycin sodium (Standard) | ≥98% | Duazomycin sodium (Standard) is the analytical standard of Duazomycin sodium (HY-105723A). This product is intended for research and analytical applications. Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) (HY-13677) in experimental allergic encephalomyelitis (EAE) without increasing toxicity. | ||||||||||||||||||||
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References
- [1]. Vogel C L, et al. Enhanced suppression of experimental allergic encephalomyelitis by combination chemotherapy with duazomycin-A and 6-mercaptopurine[J]. Proceedings of the Society for Experimental Biology and Medicine, 1969, 131(1): 251-256. [Content Brief]
- [2]. Rosenberg S, et al. Enhanced Suppression of the Secondary Immune Response by Combination of 6-Mercaptopurine ‘Duazomycin A’[J]. Nature, 1963, 199(4898): 1101-1102.
