2839627-76-6
2839627-76-6
Chemical Structure
ABCA1 inducer 1
- CAS No.: 2839627-76-6
- Formula:C24H24Cl2N2O7S2
- Molecular Weight:587.49
InChIKey: CSWGQEHEYAADCX-UHFFFAOYSA-N
SMILES: CCOC(C1=CC(NC(C2=C(C=C(S2)Cl)S(=O)(N(C3=CC(OC)=C(C=C3)OCC)C)=O)=O)=CC(Cl)=C1)=O
Biological Activity: ABCA1 inducer 1 is a nonlipogenic ABCA1 inducer. ABCA1 inducer 1 increases ABCA1 expression, enhances apolipoprotein (APOE) lipidation and reverses multiple Alzheimer’s disease (AD) phenotypes, without increasing triglycerides in E3/4FAD mice that express human APOE 3/4[1].
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ABCA1 inducer 1 | ABCA1 inducer 1 is a nonlipogenic ABCA1 inducer. ABCA1 inducer 1 increases ABCA1 expression, enhances apolipoprotein (APOE) lipidation and reverses multiple Alzheimer’s disease (AD) phenotypes, without increasing triglycerides in E3/4FAD mice that express human APOE 3/4. | |||||||||||||||||||||
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