2839639-72-2
2839639-72-2
Chemical Structure
STING modulator-4
- CAS No.: 2839639-72-2
- Formula:C17H18N8O
- Molecular Weight:350.38
IUPAC Name: 4-(4-(1-ethyl-1H-pyrazol-5-yl)-1-methyl-1H-imidazol-2-yl)-1-methyl-1H-pyrazolo[4,3-c]pyridine-6-carboxamide
InChIKey: ZWGMDXYLOOIUHN-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C=NN2C)C(C3=NC(C4=CC=NN4CC)=CN3C)=N1)N
Biological Activity: STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell[1].
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STING modulator-4 | STING modulator-4 (compound AIH05) is a competitive STING modulator with a Ki of 0.0933 μM for R232H STING. STING modulator-4 has an EC50 of >10 μM for p-IRF3 in THP-1 cell. | |||||||||||||||||||||
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