2841467-86-3
2841467-86-3
Chemical Structure
IDO1-IN-25
- CAS No.: 2841467-86-3
- Formula:C14H8Cl3NO2S
- Molecular Weight:360.64
InChIKey: QMHPTJIYGUAXKF-UHFFFAOYSA-N
SMILES: O=S(CC1=CC=C(Cl)C=C1)C(O2)=NC3=C2C=C(Cl)C(Cl)=C3
Biological Activity:
IDO1-IN-25 is a dual inhibitor of IDO1/TDO2, with IC50 values of 0.17 μM and 3.2 μM, respectively. IDO1-IN-25 can effectively inhibit the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). IDO1-IN-25 can exert anti-inflammatory effects in a mouse ear edema acute inflammation model induced by croton oil[1].
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IDO1-IN-25 | IDO1-IN-25 is a dual inhibitor of IDO1/TDO2, with IC50 values of 0.17 μM and 3.2 μM, respectively. IDO1-IN-25 can effectively inhibit the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). IDO1-IN-25 can exert anti-inflammatory effects in a mouse ear edema acute inflammation model induced by croton oil. |
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