28458-23-3
28458-23-3
Chemical Structure
Nidurufin
- CAS No.: 28458-23-3
- Formula:C20H16O8
- Molecular Weight:384.34
IUPAC Name: (2S,5S,6R)-5,7,9,11-tetrahydroxy-2-methyl-3,4,5,6-tetrahydro-2H-2,6-epoxyanthra[2,3-b]oxocine-8,13-dione
InChIKey: JJXUKZWOMSARJK-UUADDVKTSA-N
SMILES: OC1=C2C(O[C@@]3(O[C@H]2[C@H](CC3)O)C)=CC4=C1C(C5=C(O)C=C(O)C=C5C4=O)=O
Biological Activity: Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner(IC50=12.6 μM)[1].
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Nidurufin | Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner(IC50=12.6 μM). | |||||||||||||||||||||
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