284665-15-2
284665-15-2
Chemical Structure
N-Acetyl-L-aspartic acid-d3
- CAS No.: 284665-15-2
- Formula:C6H6D3NO5
- Molecular Weight:178.16
IUPAC Name: N-acetylaspartic-2,3,3-d3 acid
InChIKey: OTCCIMWXFLJLIA-YQVMVYRTSA-N
SMILES: O=C(O)C([2H])([2H])C(C(O)=O)([2H])NC(C)=O
Biological Activity: N-Acetyl-L-aspartic acid-d3 is the deuterium labeled N-Acetyl-L-aspartic acid (HY-113524). N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease)[1][2][3][4][5][6].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetyl-L-aspartic acid-d3 | 99.77% | N-Acetyl-L-aspartic acid-d3 is the deuterium labeled N-Acetyl-L-aspartic acid (HY-113524). N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease). | ||||||||||||||||||||
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N-Acetyl-L-aspartic acid (Standard) | 99.60% | N-Acetyl-L-aspartic acid (Standard) is the analytical standard of N-Acetyl-L-aspartic acid (HY-113524). This product is intended for research and analytical applications. N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease). | ||||||||||||||||||||
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N-Acetyl-L-aspartic acid | 98.07% | N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease). | ||||||||||||||||||||
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N-Carbamoyl-L-aspartic acid | 99.83% | N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura+ strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura- strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of *Saccharomyces cerevisiae* by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase. | ||||||||||||||||||||
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N-Carbamoyl-DL-aspartic acid (Standard) | 99.92% | N-Carbamoyl-DL-aspartic acid (Standard) (Ureidosuccinic acid (Standard)) is the analytical standard of N-Carbamoyl-DL-aspartic acid (HY-128425). This product is intended for research and analytical applications. N-Carbamoyl-DL-aspartic acid is a precursor of nucleic acid pyrimidines. N-Carbamoyl-DL-aspartic acid has antitumor activities. | ||||||||||||||||||||
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N-Acetylserine-d3 | N-Acetylserine-d3 is the deuterium labeled N-Acetylserine (HY-134222A). N-Acetylserine (N-Acetyl-L-serine) is a physiological inducer of cysteine biosynthesis and activator of CysB. N-Acetylserine can bind to the CysB apoprotein. N-Acetylserine stimulates cysJIH transcription in vitro. N-Acetylserine can be used in the research of SARS-CoV-2 infection. | |||||||||||||||||||||
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Nalpha-Acetyl-DL-glutamine-2,3,3,4,4-d5 | Nalpha-Acetyl-DL-glutamine-2,3,3,4,4-d5 is the deuterium labeled Nalpha-Acetyl-DL-glutamine-2,3,3,4,4. | |||||||||||||||||||||
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Acetyl-D-glutamine-d5 | Acetyl-D-glutamine-d5 (Ac-D-Gln-OH-d5) is the deuterium labeled Acetyl-D-glutamine. | |||||||||||||||||||||
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L-Aspartic acid-15N,d3 | L-Aspartic acid-15N,d3 is the 15N, deuterated-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy. | |||||||||||||||||||||
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Ac-Ala-OH-d4 | Ac-Ala-OH-d4 is the deuterium labeled Ac-Ala-OH. Ac-Ala-OH is an endogenous metabolite. | |||||||||||||||||||||
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Ac-D-Ala-OH-d4 | 99.0% | Ac-D-Ala-OH-d4 is the deuterium labeled Ac-D-Ala-OH. | ||||||||||||||||||||
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N-Acetyl-L-glutamic acid (Standard) | 99.96% | N-Acetyl-L-glutamic acid (Standard) is the analytical standard of N-Acetyl-L-glutamic acid (HY-W015240). This product is intended for research and analytical applications. N-Acetyl-L-glutamic acid is a type of glutamic acid that can serve as a component of cell culture media. When combined with media containing inorganic salts, carbohydrates, vitamins, and amino acids, N-Acetyl-L-glutamic acid plays roles in promoting cell growth, enhancing antibody production, etc. N-Acetyl-L-glutamic acid is also an endogenous metabolite that can be found in the brain. Additionally, as an IgE blocker, N-Acetyl-L-glutamic acid can be used in the research of allergic diseases. | ||||||||||||||||||||
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Ac-D-Glu-OH | Ac-D-Glu-OH is a glutamic acid derivative. | |||||||||||||||||||||
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Ac-D-Glu-OH-d5 | 99.0% | Ac-D-Glu-OH-d5 is the deuterium labeled Ac-D-Glu-OH. | ||||||||||||||||||||
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N-Acetyl-DL-aspartic acid | 99.93% | N-Acetyl-DL-aspartic acid (Ac-DL-Asp-OH) is an aspartic acid derivative. | ||||||||||||||||||||
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N-Acetyl-DL-aspartic acid-2,3,3-d3 | N-Acetyl-DL-aspartic acid-2,3,3-d3 is the deuterium labeled N-Acetyl-DL-aspartic acid-2,3,3. | |||||||||||||||||||||
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(S)-2-acetamido-4-amino-4-oxobutanoic acid | 98.0% | (S)-2-acetamido-4-amino-4-oxobutanoic acid is a metabolite. (S)-2-acetamido-4-amino-4-oxobutanoic acid can be used in the research of decompensated liver cirrhosis. | ||||||||||||||||||||
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N-Methyl-DL-aspartic acid (Standard) | ≥98% | N-Methyl-DL-aspartic acid is a glutamate analogue and a NMDA receptor agonist and can be used for neurological diseases research. | ||||||||||||||||||||
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Gly-Asp | Gly-Asp is a Glycine (HY-Y0966) derivative. | |||||||||||||||||||||
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Ac-D-Asn-OH | Ac-D-Asn-OH (N2-Acetyl-D-asparagine) is the N2-acetylated derivative of D-Asparagine (HY-W010378). Ac-D-Asn-OH serves as an intermediate for peptide synthesis in relevant research. | |||||||||||||||||||||
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Gly-Asp hydrate | 98.0% | Gly-Asp hydrate is a Glycine (HY-Y0966) derivative. | ||||||||||||||||||||
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2-(Carbamoylamino)pentanedioic acid-d5 | 2-(Carbamoylamino)pentanedioic acid-d5 (N-carbamoylglutamic acid-d5) is the deuterium labeled 2-(Carbamoylamino)pentanedioic acid (HY-W169233). | |||||||||||||||||||||
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(-)-Aspartic acid-d3 | 99.92% | (-)-Aspartic acid-d3 ((R)-Aspartic acid-d3) is the deuterium labeled (-)-Aspartic acid (HY-42068). (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system. | ||||||||||||||||||||
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References
- [1]. Buniatian HC, et al. The participation of N-acetyl-L-aspartic acid in brain metabolism. J Neurochem. 1965 Aug;12(8):695-703. [Content Brief]
- [2]. Sreekumar A, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. [Content Brief]
- [3]. Karaman S, et al. Subchronic oral toxicity assessment of N-acetyl-L-aspartic acid in rats. Food Chem Toxicol. 2011 Jan;49(1):155-65. [Content Brief]
- [4]. Karaman S, et al. Two-generation reproductive and developmental toxicity assessment of dietary N-acetyl-L-aspartic acid in rats. Food Chem Toxicol. 2011 Dec;49(12):3192-205. [Content Brief]
- [5]. Delaney B, et al. Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague-Dawley rats. Food Chem Toxicol. 2008 Jun;46(6):2023-34. [Content Brief]
- [6]. Birken DL, et al. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev. 1989 Spring;13(1):23-31. [Content Brief]
