2851480-01-6
2851480-01-6
Chemical Structure
Keap1-Nrf2-IN-4
- CAS No.: 2851480-01-6
- Formula:C26H34N2O
- Molecular Weight:390.56
IUPAC Name: 1-cinnamyl-N-(4-pentylphenyl)piperidine-4-carboxamide
InChIKey: UZQSNIXFIVEVET-XYOKQWHBSA-N
SMILES: CCCCCC1=CC=C(C=C1)NC(C2CCN(CC2)C/C=C/C3=CC=CC=C3)=O
Biological Activity: Keap1-Nrf2-IN-4 is a potent neddylation inhibitor. Keap1-Nrf2-IN-4 exhibits potent anti-proliferation activity against MGC-803 cells (IC50=2.55 µM). Keap1-Nrf2-IN-4 blocks the migration ability and induces apoptosis of gastric cancer cells. Keap1-Nrf2-IN-4 inhibits tumor growth without obvious toxicity[1].
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Keap1-Nrf2-IN-4 | Keap1-Nrf2-IN-4 is a potent neddylation inhibitor. Keap1-Nrf2-IN-4 exhibits potent anti-proliferation activity against MGC-803 cells (IC50=2.55 µM). Keap1-Nrf2-IN-4 blocks the migration ability and induces apoptosis of gastric cancer cells. Keap1-Nrf2-IN-4 inhibits tumor growth without obvious toxicity. | |||||||||||||||||||||
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